Chondromyxoid Fibroma

General characteristics

Chondromyxoid fibroma is composed of three principal elements: chondroid, fibrous, and myxoid tissue. It is the least common of the benign cartilaginous bone neoplasms.


There is a male predominance, with a male-to-female ratio of 1.5 to 2:l.


The tumor tends to occur around the knee joint but can involve any bone. The tumor is usually solid but may contain cystic or hemorrhagic areas.


On MR images, signal intensities of this tumor vary with the proportions of chondroid, fibrous, and myxoid tissues present. CT may be better than MRI in delineating matrix calcification and sclerosis around the tumor.