Oligodendroglioma

General view



1

Fig.1 General view of Olygodendroglioma

Epidemiology

Oligodendrogliomas account for 5-10% of all CNS tumors. Age the interval of occurrence is 3-80 years, the peak age is 40-50 years.

Morphology

Oligodendroglioma (ODG) is a tumor without clear boundaries, with a frequent presence of petrifications (in 90% of cases), possibly the presence of cysts. Necrosis and hemorrhages are not typical for benign tumors, but are possible in anaplastic forms. Macroscopically, the tumor is relatively well defined, but infiltration is present outside apparently unchanged zones. There is a tendency to involve the cerebral cortex and change adjacent areas of the cranial vault with bone thinning (by the type of atrophy due to pressure).

2

Fig.2 Morphology of Olygodendroglioma

Tumor, as a rule, affects both gray and white matter. [48]. Pure ODG contains at least 75% of oligodendroglial cells [48]. The nearest edema caused by the tumor is minimal [137].

On MRI, the tumor has an elevated MR signal of T2 and Flair, decreased by T1, in the presence of large petrification, foci of loss of the MR signal are determined. Diffusion in the affected area is not limited, there are no changes on the DWI and ADC. On CT, the tumor is slightly hypodense or isodense, but the presence of petrificates increases the density of the tumor from 80 to 100 HU. Although the calcified areas are less visible than on CT, they can become apparent in the gradient echo (T2 *). In addition, petrificata can be considered as hyperintensive regions on T1 due to the paramagnetic effects of calcium ions [137].




The author of the article: radiologist, Ph.D. Vlasov Evgeniy Alexandrovich

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