Dysembryoplastic neuroepithelial tumor

General characteristics

Dysembryoplastic neuroepithelial tumor (WHO grade I) is a very uncommon, slow-growing benign, usually supratentorial, neuronal–glial neoplasm that occurs primarily in children and young adults with a long-standing history of partial seizures (Dauman-Duport et al. 2000).

Imaging and Location

This tumor may develop in any part of the supratentorial cortex, but it has a predilection for the temporal lobe where a high intensity mass lesion on T2-weighted scans is the typical MRI finding. Some dysembryoplastic neuroepithelial tumors may present cystic components and calcifications, which makes it difficult to distinguish them from oligodendrogliomas or oligoastrocytomas.

Clinical symptoms

In one study, almost 90% of lesions associated with drug-resistant seizures were found to be dysembryoplastic neuroepithelial tumors.


  1. M.F. Reiser, W. Semmler, H. Hricak (Eds.) "Magnetic Resonance Tomography", Springer 2008