Desmoplastic infantile astrocytoma (DIA) and Desmoplastic infantile ganglioglioma (DIG)

Desmoplastic infantile astrocytoma (DIA) and desmoplastic infantile ganglioglioma (DIG) (WHO grade I) are large, cystic tumors of infants that involve the superficial cerebral cortex and leptomeninges, often attached to dura (Nikas et al. 2004).

These rare neoplasms typically occur within the first 2 years of life. The lesions are typically partially cystic, and contain a variable neuronal component in addition to neoplastic astrocytes. The histology of the tumors is responsible for the heterogeneous appearance on MRI.


  1. M.F. Reiser, W. Semmler, H. Hricak (Eds.) "Magnetic Resonance Tomography", Springer 2008