Central neurocytoma (WHO grade I, II) is a recently described relatively benign intraventricular neoplasm that is composed of round cells with neuronal differentiation (Figarella-Branger et al. 2000).
In a large surgical series, incidence ranged from 0.25 to 0.5% of all brain tumors. Almost 75% of these types of tumors are diagnosed between the ages of 20 and 40 years, with hydrocephalus as the leading clinical finding.
Imaging and Location
On imaging studies, these tumors present typical characteristics with intraventricular location and attachment of the septum pellucidum (Wichman et al. 1991; Bolen et al. 1989). While calcifications can only be shown with CT, the mass lesions are homogeneous and isointense to gray matter on T2-weighted MRI.
Enhancement can be seen in most of the cases, which allows a differential diagnosis from heterotopic gray matter.
The clinical course of central neurocytoma is benign; the treatment of choice is complete surgical resection.
- M.F. Reiser, W. Semmler, H. Hricak (Eds.) "Magnetic Resonance Tomography", Springer 2008